منابع مشابه
Dermatitis herpetiformis with fibrillar IgA deposition and unusual histologic findings
DH: dermatitis herpetiformis DIF: direct immunofluorescence INTRODUCTION Dermatitis herpetiformis (DH) is an autoimmune, subepidermal blistering disease associated with gluten sensitivity. It commonly manifests as intensely pruritic papules and vesicles on the extensor surfaces of extremities in a symmetric distribution. Classic histologic findings and data from direct immunofluorescent (DIF) s...
متن کاملIgA Nephropathy, Celiac Disease and Dermatitis Herpetiformis: A Rare Triad
IgA nephropathy was found associated with celiac disease and dermatitis herpetiformis in a two years old male child at our center. This observed association widen the spectrum of the diseases that have been reported to coexist with IgA nephropathy.
متن کاملSmall bowel transglutaminase 2-specific IgA deposits in dermatitis herpetiformis.
Dermatitis herpetiformis (DH) is an extraintestinal manifestation of coeliac disease. Untreated coeliac disease patients are known to have transglutaminase 2 (TG2)-targeted IgA deposits in the small bowel mucosa. To evaluate whether similar intestinal IgA deposits are also present in DH and whether the deposits disappear with gluten-free diet, 47 untreated and 27 treated DH patients were studie...
متن کاملDermatitis herpetiformis.
Dermatitis herpetiformis (DH) is an autoimmune, pleiomorphic, papulovesicular disorder associated with celiac disease and gluten sensitivity. DH is characterized by subepidermal bullae on hematoxylin and eosin staining and granular immunoglobulin A deposits in the dermal papillae using the direct immunofluorescence method. Antibodies to tissue transglutaminase and epidermal transgulatminase can...
متن کاملDermatitis herpetiformis and vitiligo.
Dermatitis herpetiformis (DH) is a rare immunobullous disorder of the skin that is associated with gluten hypersensitivity. Subepidermal IgA-type antibody deposition against tissue transglutaminase leads to dense neutrophilic microabscess and eventually into vesicles in dermal papillae, which may occasionally merge into bullae. Being a subepidermal vesiculobullous disorder, DH is frequently ass...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1978
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12547299